Publications:
Nikolaivits et al. 2019


scientific article | Marine Drugs

Unraveling the detoxification mechanism of 2, 4-dichlorophenol by marine-derived mesophotic symbiotic fungi isolated from marine invertebrates

Nikolaivits E, Agrafiotis A, Termentzi A, Machera K, Le Goff G, Álvarez P, Chavanich S, Benayahu Y, Ouazzani J, Fokialakis N, Topakas E


Abstract

Chlorophenols (CPs) are environmental pollutants that are produced through various anthropogenic activities and introduced in the environment. Living organisms, including humans, are exposed to these toxic xenobiotics and suffer from adverse health effects. More specifically, 2,4-dichlorophenol (2,4-DCP) is released in high amounts in the environment and has been listed as a priority pollutant by the US Environmental Protection Agency. Bioremediation has been proposed as a sustainable alternative to conventional remediation methods for the detoxification of phenolic compounds. In this work, we studied the potential of fungal strains isolated as symbionts of marine invertebrates from the underexplored mesophotic coral ecosystems. Hence, the unspecific metabolic pathways of these fungal strains are being explored in the present study, using the powerful analytical capabilities of a UHPLC-HRMS/MS. The newly identified 2,4-DCP metabolites add significantly to the knowledge of the transformation of such pollutants by fungi, since such reports are scarce.

Keywords
Meta-data
Depth range
30- 152 m

Mesophotic “mentions”
11 x (total of 3974 words)

Classification
* Presents original data
* Focused on 'mesophotic' depth range
* Focused on 'mesophotic coral ecosystem'
* Focused on 'temperate mesophotic ecosystem'

Fields
Biomedicine
Disturbances

Focusgroups
Fungi

Locations
Israel - Red Sea
Israel - Mediterranean Sea
India - Andaman and Nicobar Islands

Platforms
Land-based

Author profiles